Stem cell transplantation, also called bone marrow transplantation, is currently being used in the treatment of leukemia, lymphoma, multiple myeloma, various organ cancers, inadequate bone marrow status, hereditary anemia, immune deficiencies and hereditary metabolic diseases.
Stem cell bone marrow, peripheral blood or cord can be blood. Although bone marrow is used as a source of stem cells in the first transplants, 75% of the patients have peripheral blood stem cell transplantation. The stem cell is collected from the cord blood as soon as the baby is born. Collected stem cells are stored under sterile conditions.
Stem cell transplants are defined as autologous or allogeneic transport.
Autologous transplantation is the process of collecting and storing the patient’s own stem cells and then returning them to the patient. The most common uses of autologous stem cell transplantation are multiple myeloma, non-Hodgkin and non-Hodgkin lymphoma, neuroblastoma, solid tumors such as germ cell tumors, and acute leukemias.
Allogeneic transplantation is the process of delivering stem cells collected from a fully compatible donor other than the patient. The most common uses of allogeneic stem cell transplantation are acute leukemia, myelodysplastic syndrome, lymphoproliferative diseases, aplastic anemia, thalassemia and hereditary metabolic diseases.
Transmitter / donor; The tissue is compatible, non-sibling, relative or non-relative. Donating stem cells don’t subtract from the donor. The most common side effects are bone pain, muscle pain, and flu-like symptoms and are treated symptomatically.
Our bone marrow transplantation center serves adult patients. Autologous transport process; The patient begins with the collection and storage of its own stem cell. Following the administration of the high-dose chemotherapy, which we call the patient’s preparation regimen, the stem cells are dissolved. Within two weeks, the stem cell is placed in the bone marrow, ie engraftment, the patient’s cell number returns to normal and is discharged from the transport unit. The allogeneic transplantation process starts with the search for a tissue group compatible donor for the transplant candidate. If the patient and the appropriate donor are suitable for transplantation, the patient is given the stem cells collected from the donor after the high-dose chemotherapy which we call the preparation regime is given. Within three weeks, the stem cell is nested in the bone marrow, ie engraftment, the patient’s cell number returns to normal and is discharged from the transplantation unit.
Stem cell transplantation is a teamwork product. With an experienced transport team and ideal physical conditions, the process of transport requiring intensive labor for the patients and their relatives is successfully completed.